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Tyrosinase‐Like Reactivity in a Cu III 2 (μ‐O) 2 Species
Author(s) -
Company Anna,
Palavicini Sara,
GarciaBosch Isaac,
MasBallesté Ruben,
Que Lawrence,
RybakAkimova Elena V.,
Casella Luigi,
Ribas Xavi,
Costas Miquel
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200800229
Subject(s) - hydroxylation , reactivity (psychology) , tyrosinase , intermolecular force , chemistry , stereochemistry , molecule , enzyme , organic chemistry , medicine , alternative medicine , pathology
Center stage : Intermolecular phenolate binding to and hydroxylation by a bis(μ‐oxo) dicopper(III) species demonstrate the ability of this core to perform tyrosinase‐like reactivity. Kinetic analysis of the hydroxylation reaction (see scheme) shows remarkable similarities to aromatic hydroxylation reactions performed by side‐on peroxo‐type dicopper(II) species.