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Cover Picture: Biology‐Oriented Synthesis of Stereochemically Diverse Natural‐Product‐Derived Compound Collections by Iterative Allylations on a Solid Support (Chem. Eur. J. 12/2007)
Author(s) -
Umarye Jayant D.,
Leßmann Torben,
García Ana B.,
Mamane Victor,
Sommer Stefan,
Waldmann Herbert
Publication year - 2007
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200790036
Subject(s) - diastereomer , natural product , substructure , cover (algebra) , stereochemistry , chemistry , combinatorial chemistry , engineering , mechanical engineering , structural engineering
α,β‐Unsaturated δ‐lactones with multiply oxygenated side chains are a substructure found in a group of natural products with a broad range of biological activity. In their Full Paper on page 3305 ff., H. Waldmann et al. describe the parallel synthesis of all eight diastereomers of cryptocarya diacetate by asymmetric allylation reactions on a solid support with chiral allylboranes.