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Chiral Bidentate Bis(N‐Heterocyclic Carbene)‐Based Palladium Complexes Bearing Carboxylate Ligands: Highly Effective Catalysts for the Enantioselective Conjugate Addition of Arylboronic Acids to Cyclic Enones
Author(s) -
Zhang Tao,
Shi Min
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200701982
Subject(s) - carbene , denticity , conjugate , chemistry , palladium , enantioselective synthesis , carboxylate , chelation , catalysis , adduct , medicinal chemistry , polymer chemistry , stereochemistry , organic chemistry , crystal structure , mathematics , mathematical analysis
Abstract Axially chiral cis ‐chelated bidentate bis(N‐heterocyclic carbene)–palladium(II) complexes with two weakly coordinating carboxylate ligands are effective catalysts for the asymmetric conjugate addition of arylboronic acids to cyclic enones, producing the corresponding adducts in moderate‐to‐high yields and with good‐to‐high enantioselectivities, in most cases under mild conditions.