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Cover Picture: Antibiotic Resistance: Mono‐ and Dinuclear Zinc Complexes as Metallo‐β‐Lactamase Mimics (Chem. Eur. J. 30/2006)
Author(s) -
Tamilselvi A.,
Nethaji Munirathinam,
Mugesh G.
Publication year - 2006
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200690095
Subject(s) - bioinorganic chemistry , antibiotics , cover (algebra) , ring (chemistry) , zinc , chemistry , bacteria , antibiotic resistance , antibacterial activity , combinatorial chemistry , stereochemistry , microbiology and biotechnology , biology , biochemistry , organic chemistry , genetics , mechanical engineering , engineering
Survival techniques have been evolved by bacteria to afford resistance to currently available antibiotics. One of these methods is the generation of β‐lactamases that hydrolyze the β‐lactam ring in antibiotics, as shown in the cover picture. In their Full Paper on page 7797 ff., G. Mugesh et al. describe a novel bioinorganic system as a functional mimic of the antibacterial‐resistant enzyme metallo‐β‐lactamase.