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A New Approach to Enantiopure C 3 ‐Symmetric Molecules
Author(s) -
Castaldi M. Paola,
Gibson Susan E.,
Rudd Matthew,
White Andrew J. P.
Publication year - 2005
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200501031
Subject(s) - enantiopure drug , ruthenium , molecule , substrate (aquarium) , chemistry , triol , stereochemistry , combinatorial chemistry , combinatorics , computational chemistry , mathematics , enantioselective synthesis , organic chemistry , catalysis , diol , oceanography , geology
Chiral base chemistry has been used to create three chiral centres in one pot on a C 3 ‐symmetric substrate. The potential of this new approach to C 3 ‐symmetric molecules is exemplified by the creation of an enantiopure C 3 v ‐symmetric triol, triphosphane and tripyridine. A ruthenium complex of the last compound has been studied by X‐ray crystallography.