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High Resolution 1 H NMR Structural Studies of Sucrose Octaacetate in Supercritical Carbon Dioxide
Author(s) -
Chandrika Baby,
Schnackenberg Laura K.,
Raveendran Poovathinthodiyil,
Wallen Scott L.
Publication year - 2005
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200500215
Subject(s) - supercritical carbon dioxide , supercritical fluid , carbon dioxide , chemistry , resolution (logic) , sucrose , organic chemistry , computer science , artificial intelligence
High pressure (HP), high resolution (HR), proton nuclear magnetic resonance ( 1 H NMR) spectroscopy has been utilized for the first time to investigate the solution structure of a carbohydrate based system, sucrose octaacetate (SOA), in supercritical CO 2 . The studies indicate that the average solution state conformation of the α‐ D ‐Glucopyranosyl ring of SOA in scCO 2 medium is consistent with the 4 C 1 chair form, while the β‐ D ‐fructofuranosyl ring adopts an envelope conformation. The investigations also suggest that scCO 2 is a promising medium to study the solution structure and conformation of acetylated sugar systems. Spectral manifestations of a specific interaction between the acetate methyl protons and CO 2 molecules are also presented.