Premium
Cover Picture: Expanded Utility of the Native Chemical Ligation Reaction (Chem. Eur. J. 19/2004)
Author(s) -
Yeo Dawn S. Y.,
Srinivasan Rajavel,
Chen Grace Y. J.,
Yao Shao Q.
Publication year - 2004
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200490064
Subject(s) - intein , native chemical ligation , ligation , chemistry , thioester , cover (algebra) , stereochemistry , combinatorial chemistry , biochemistry , microbiology and biotechnology , biology , cysteine , engineering , enzyme , gene , rna splicing , mechanical engineering , rna
The cover picture shows the X‐ray structure of Sce VMA intein from Saccharomyces cerevisiae in the background. This intein has been extensively modified to overexpress proteins that have a C‐terminal thioester, which is the key component for the so‐called "Native Chemical Ligation Reaction" shown in the foreground. More details could be found in the article by S. Q. Yao et al. on p. 4664 ff.