Premium
Cover Picture: Self‐Assembled Monolayers of Dendritic Polyglycerol Derivatives on Gold That Resist the Adsorption of Proteins (Chem. Eur. J. 11/2004)
Author(s) -
Siegers Conrad,
Biesalski Markus,
Haag Rainer
Publication year - 2004
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200490036
Subject(s) - chemistry , monolayer , monomer , linker , covalent bond , polymer chemistry , surface plasmon resonance , adsorption , thermal stability , self assembly , self assembled monolayer , combinatorial chemistry , protein adsorption , chemical engineering , organic chemistry , nanotechnology , materials science , polymer , nanoparticle , biochemistry , computer science , engineering , operating system
The cover picture shows the formation of a self‐assembled monolayer of dendritic polyglycerol on a semitransparent gold‐film and its high protein resistant properties. The polyglycerol derivative is readily obtained by ester coupling with thioctic acid, which provides a stable covalent linker to the gold surface. Several dendritic polyglycerol derivatives as well as the monomer equivalent (thioglycerol) were screened for their protein resistant properties with a fibrinogen solution by surface plasmon resonance spectroscopy (SPR). The excellent protein resistant properties and the high thermal stability of this new material, which classifies for the coating of biomedical devices, is reported in detail by R. Haag et al. on p. 2831 ff.