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Optically Active Oligomer Units in Aggregates of a Highly Unsaturated, Optically Inactive Carotenoid Phospholipid
Author(s) -
Foss Bente Jeanette,
Sliwka HansRichard,
Partali Vassilia,
Köpsel Christian,
Mayer Bernhard,
Martin HansDieter,
Zsila Ferenc,
Bikadi Zsolt,
Simonyi Miklos
Publication year - 2005
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200401191
Subject(s) - glycerophospholipids , amphiphile , monomer , phospholipid , histone octamer , enantiomer , chemistry , oligomer , optically active , supramolecular chemistry , stereochemistry , photochemistry , organic chemistry , biochemistry , molecule , polymer , copolymer , nucleosome , membrane , gene , histone
Enantiomers of glycerophospholipids show low or no optical activity. Accordingly, optical activity was not observed with the R enantiomer of a highly unsaturated carotenoyl lysophospholipid in solution. In spite of this, strong Cotton effects are detected in water. The amphiphilic carotenoid–phospholipid monomers associate to form aggregates, whose optical activity is attributed to oligomeric entities. These small helical assemblies cannot exist independently. Yet, the calculated octamer represents the simplest repeating primary unit that sufficiently expresses the absorption properties and supramolecular optical activity.