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Maleimido‐Terminated Self‐Assembled Monolayers
Author(s) -
Wang Yayun,
Cai Jun,
Rauscher Hubert,
Behm Rolf Jürgen,
Goedel Werner A.
Publication year - 2005
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200400896
Subject(s) - trichlorosilane , monolayer , chemistry , x ray photoelectron spectroscopy , self assembled monolayer , alkyl , conjugate , polymer chemistry , thiol , silicon , organic chemistry , chemical engineering , mathematical analysis , biochemistry , mathematics , engineering
Four approaches have been explored for the preparation of maleimido‐functionalized self‐assembled monolayers (SAMs) on silicon. SAMs prepared by self‐assembly of maleimido‐functionalized alkyltrichlorosilanes (11‐maleimido‐undecyl‐trichlorosilane) on oxide‐covered silicon yield higher signals from maleimido functionalities in ATR‐IR (attenuated total reflection IR) spectroscopy and XPS (X‐ray photoelectron spectroscopy) than the other three methods. The surface composition of maleimido groups was tailored further by the formation of mixed monolayers with nonfunctionalized alkyltrichlorosilanes (decyltrichlorosilane). The order of the alkyl chains within the monolayers only slightly depends on the composition of the mixed monolayers. We utilized the maleimido‐terminated SAMs to bind various nucleophilic compounds, alkylamines, alkylthiols, and thiol‐tagged DNA oligonucleotides by means of conjugate addition.