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Synthesis of an Amino‐Functionalized Model of the Fe‐Only Hydrogenase Active Site
Author(s) -
Salyi Szabolcs,
Kritikos Mikael,
Åkermark Björn,
Sun Licheng
Publication year - 2003
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200390058
Subject(s) - active site , hydrogenase , supramolecular chemistry , chemistry , linkage (software) , electron transfer , stereochemistry , combinatorial chemistry , crystallography , crystal structure , enzyme , biochemistry , photochemistry , gene
A dinuclear 2Fe2S mimic 6 of the active site of the Fe‐only hydrogenases has been synthesized. Complex 6 contains a free amino group which enables linkage to a protein backbone or to a redox active species for the study of electron transfer processes in proteins or in supramolecular systems. The structures of the complex 6 and its Boc‐protected precursor 5 could be verified by X‐ray crystallography.