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Catalytic Ionic Hydrogenations
Author(s) -
Bullock R. Morris
Publication year - 2004
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200305639
Subject(s) - ketone , catalysis , hydride , chemistry , noyori asymmetric hydrogenation , ionic bonding , metal , cationic polymerization , ionic liquid , molybdenum , organic chemistry , inorganic chemistry , photochemistry , ruthenium , ion
Catalytic ionic hydrogenation of ketones occurs by proton transfer to a ketone from a cationic metal dihydride, followed by hydride transfer from a neutral metal hydride. This contrasts with traditional catalysts for ketone hydrogenation that require binding of the ketone to the metal and subsequent insertion of the ketone into a MH bond. Ionic hydrogenation catalysts based on the inexpensive metals molybdenum and tungsten have been developed based on mechanistic understanding of the individual steps required in the catalytic reaction.