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Chromo‐ and Fluororeactands: Indicators for Detection of Neutral Analytes by Using Reversible Covalent‐Bond Chemistry
Author(s) -
Mohr Gerhard J.
Publication year - 2004
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200305524
Subject(s) - analyte , chemistry , covalent bond , absorbance , molecule , photochemistry , fluorescence , organic chemistry , chromatography , physics , quantum mechanics
Chromo‐ and fluororeactands are indicator dyes that allow the optical detection of electrically neutral analytes. Unlike complexing agents such as calixarenes, cyclodextrines or cyclophanes, reactands form a reversible covalent bond with the analyte molecule. This chemical reaction causes strong changes in absorbance or fluorescence. In this article reactands for analytes such as amines, alcohols, aldehydes, saccharides, carbon dioxide and sulfur dioxide are presented. Methods to enhance the sensitivity of the reactands as well as the operational and shelf lives of the corresponding optical sensors are discussed.