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The Impact of Membrane Composition and Co‐Drug Synergistic Effects on Vancomycin Association with Model Membranes from Electrochemical Impedance Spectroscopy
Author(s) -
Sarangi Nirod Kumar,
Stalcup Apryll,
Keyes Tia E.
Publication year - 2020
Publication title -
chemelectrochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.182
H-Index - 59
ISSN - 2196-0216
DOI - 10.1002/celc.202001281
Subject(s) - dielectric spectroscopy , vancomycin , membrane , lipid bilayer , penetration (warfare) , rifampicin , drug , chemistry , electrochemistry , materials science , biophysics , pharmacology , antibiotics , medicine , biochemistry , bacteria , biology , electrode , engineering , genetics , staphylococcus aureus , operations research
Invited for this month's cover picture is the group of Prof. Tia E. Keyes. The cover picture shows the interaction of vancomycin at microcavity spanned lipid bilayer membranes—a versatile biomimetic platform for drug–lipid interaction studies. Using electrochemical impedance spectroscopy, we show interaction and penetration of the drug vancomycin through lipid membrane is promoted when it is co‐administered with rifampicin. Read the full text of the Article at 10.1002/celc.202000818.