Premium
Cover Feature: Application of Electrochemical Processes to Classical Iodocyclisation: Utility for Selectivity and Mechanistic Insight (ChemElectroChem 23/2019)
Author(s) -
Li Diyuan,
Seavill Peter W.,
Wilden Jonathan D.
Publication year - 2019
Publication title -
chemelectrochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.182
H-Index - 59
ISSN - 2196-0216
DOI - 10.1002/celc.201901836
Subject(s) - nucleophile , electrochemistry , graphite , chemistry , halogen , zinc , iodide , selectivity , halogenation , cover (algebra) , combinatorial chemistry , alkene , ring (chemistry) , ion , inorganic chemistry , organic chemistry , electrode , catalysis , mechanical engineering , engineering , alkyl
The Cover Feature illustrates the ‘on‐demand’ release of Zn 2+ ions from a zinc‐metal‐coated graphite electrode. Once the zinc has been exhausted, oxidation of iodide ions can occur to liberate molecular iodine. This dual‐oxidative process can be harnessed to affect the iodocyclisation of phenolic nucleophiles onto a pendant alkene. This electrochemical approach allows a steady, low concentration delivery of the halogen into the solution which helps to prevent unwanted iodination of the activated aromatic ring. More information can be found in the Article by D. Li et al. on page 5829 in Issue 23, 2019 (DOI: 10.1002/celc.201901502).