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Direct Anodic Dehydrogenative Cross‐ and Homo‐Coupling of Formanilides
Author(s) -
Schulz Lara,
Franke Robert,
Waldvogel Siegfried R.
Publication year - 2018
Publication title -
chemelectrochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.182
H-Index - 59
ISSN - 2196-0216
DOI - 10.1002/celc.201800422
Subject(s) - electrochemistry , anode , group (periodic table) , coupling (piping) , atom (system on chip) , chemistry , materials science , combinatorial chemistry , computer science , metallurgy , organic chemistry , electrode , embedded system
The direct anodic dehydrogenative C−C cross‐ and homo‐coupling of formanilides is reported. This exceptional electrochemical synthesis allows one to prepare a broad variety of non‐symmetrical and symmetrical 2,2′‐diformamidobiphenyls as well as 2‐formamido‐2′‐amidobiphenyls. By applying an easy and simple to perform metal‐ and oxidizer‐free electrochemical protocol, and the formyl group as a highly atom‐economic amino‐protecting group, an important contribution to a sustainable and green‐minded chemistry was achieved.