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Photoelectrochemical Probing of Cellular Interfaces and Evaluation of Cellular H 2 S Production Based on In Situ‐Generated CdS‐Enhanced TiO 2 Nanotube Heterostructures
Author(s) -
Zhu YuanCheng,
Wang Qian,
Zhang LiBin,
Zhao WeiWei,
Xu JingJuan,
Chen HongYuan
Publication year - 2017
Publication title -
chemelectrochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.182
H-Index - 59
ISSN - 2196-0216
DOI - 10.1002/celc.201700149
Subject(s) - in situ , heterojunction , materials science , nanotechnology , nanotube , interfacing , optoelectronics , chemistry , computer science , carbon nanotube , organic chemistry , computer hardware
Judiciously integrated nanostructured materials/cellular interfaces could be applied for various applications including physiological monitoring. Physiological H 2 S is the third most important endogenously generated gasotransmitter and is believed to be related with many diseases. This work reports the novel photoelectrochemical (PEC) probing of cellular interfaces and the evaluation of cellular H 2 S production based on in situ‐generated CdS‐enhanced TiO 2 nanotube (NT) heterostructures. We chose the TiO 2 NT array in particular, owing to its structure of regular oriented vertical NTs (which permits fast directional charge transport) and its substantial inner cavity (which guarantees the highly efficient guest loading and molecule capture). HepG2 cells directly grown on and interfacing with the TiO 2 NTs are then used for the activation of the TiO 2 NTs through the CdS generated in situ on the TiO 2 NTs. Owing to the aforementioned unique properties of TiO 2 NTs, even small amounts of in situ‐generated CdS could be detected and result in apparent electrical signals. To the best of our knowledge, such TiO 2 NT‐based in situ PEC probing of cellular interfaces and evaluation of H 2 S cellular production have not previously been reported.