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Poisoning of Highly Porous Platinum Electrodes by Amino Acids and Tissue Fluid Constituents
Author(s) -
Köhler Christian,
Bleck Lena,
Frei Maxi,
Zengerle Roland,
Kerzenmacher Sven
Publication year - 2015
Publication title -
chemelectrochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.182
H-Index - 59
ISSN - 2196-0216
DOI - 10.1002/celc.201500215
Subject(s) - platinum , porosity , electrode , chemistry , chemical engineering , biochemistry , organic chemistry , engineering , catalysis
The first comprehensive study of the poisoning behavior of physiological amino acids and important tissue fluid constituents on porous platinum electrodes was performed. On the basis of chronoamperometry under physiological conditions, the results are highly relevant for the development of enzyme‐free implantable glucose fuel cells and possibly also glucose sensors. The strongest poisoning was exhibited by positively charged alkaline amino acids and by some of the neutral amino acids, as well as by uric acid and creatinine. In contrast to previous work, sulfur‐containing amino acids showed no poisoning effect. This was explained by the use of highly porous platinum electrodes in the current study and experimental methods that were more relevant for practical applications. Furthermore, comprehensive analysis regarding the degree of recovery in the absence of poisoning species and the extent of electrode regeneration by cyclic voltammetry was performed for each of the amino acids and physiological substances.