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Monitoring Amyloid Sup35NM Growth with Label‐Free Electrical Detection Using a Field‐Effect Transistor Biosensor
Author(s) -
Hideshima Sho,
Wustoni Shofarul,
Kuroiwa Shigeki,
Nakanishi Takuya,
KoikeTakeshita Ayumi,
Osaka Tetsuya
Publication year - 2014
Publication title -
chemelectrochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.182
H-Index - 59
ISSN - 2196-0216
DOI - 10.1002/celc.201300151
Subject(s) - biosensor , field effect transistor , nanotechnology , amyloid (mycology) , transistor , materials science , amyloid β , chemistry , biophysics , optoelectronics , biology , medicine , engineering , electrical engineering , voltage , pathology , inorganic chemistry , disease
Semiconductor biosensing: An electrical assay based on the field‐effect transistor (FET) is developed for the detection of fibrous amyloid proteins without any labels. This assay distinguishes amyloid proteins possessing the cross‐β structure, and thereby monitors amyloid growth.