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Standardization of a newly designed vibrating capillary apparatus for the preparation of microcapsules
Author(s) -
Ghosal Swapan Kumar,
Talukdar Prasanta,
Pal Tapan Kumar
Publication year - 1993
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.270160607
Subject(s) - capillary action , diffusion , coating , polymer , chemistry , gelatin , chromatography , analytical chemistry (journal) , materials science , chemical engineering , composite material , thermodynamics , organic chemistry , physics , engineering
Vibrating capillary apparatus (VCA) was designed and constructed for the preparation of sulphamethoxazole (SMZ) microcapsules using gelatin as a coating polymer. The microcapsules were characterized by physico‐chemical methods. The apparent diffusion coefficient D a and diffusion rate constant K BL of the drug were measured at pH of 1.2 and 7.2. Better controlled release products were obtained in the VCA.