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A new process for indirect gas supply by means of perfluorinated polyethers
Author(s) -
Schäfer Hans,
Bayer Thomas,
Buchholz Rainer,
Kühlein Klaus,
Schlingmann Merten,
Wullbrandt Dieter
Publication year - 1991
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.270140211
Subject(s) - process engineering , hydrocarbon , industrial gas , carbon dioxide , mass transfer , syngas , chemistry , waste management , chemical engineering , process (computing) , environmental science , materials science , organic chemistry , engineering , chromatography , hydrogen , mechanical engineering , gas turbines , computer science , operating system
A new process has been developed for indirect gas supply for culturing shear sensitive cells by means of a perfluorinated hydrocarbon. Hostinert 216, a perfluorinated polyether, was used as oxygen and carbon dioxide carrier. Hydrodynamics and mass transfer, required for industrial implementation, were investigated in a drop column. Based on the knowledge, obtained with indirect gas supply, it has been possible to construct a waste‐gas free sterile pilot plant. Correlations derived from performed measurements permit design of and scale‐up to an industrial plant.