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Acetonitrile Recovery by Distillation Techniques Combined with Salting‐Out or Sugaring‐Out in Tandem
Author(s) -
Mendonça da Silva Amorim Patrícia,
Busko Di Vitta Patricia,
Converti Attilio,
Pinheiro de Souza Oliveira Ricardo
Publication year - 2021
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.202000584
Subject(s) - acetonitrile , chemistry , salting out , chromatography , distillation , aqueous solution , extractive distillation , organic chemistry
Acetonitrile recovery from a residual aqueous solution was performed by different techniques. Particularly, a residual acetonitrile‐water solution used in high‐performance liquid chromatography analyses at the School of Pharmaceutical Sciences of the University of São Paulo was investigated with the aim to identify the most feasible way to treat such a waste and recover acetonitrile within its dependencies. Three procedures were set up and tested, which consisted of different combinations of well‐known separation techniques, such as fractional distillation, cooling, salting‐out, and sugaring‐out. Cooling followed by distillation and subsequent addition of calcium chloride allowed to recover the highest amount of acetonitrile with a purity greater than 95 %.