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Synthesis of Isopropyl Palmitate by Lipase Immobilized on a Magnetized Polymer Matrix
Author(s) -
Silva Mateus V. C.,
Rosa Cintia M. R.,
Aguiar Leandro G.,
Oliveira Pedro C.,
Castro Heizir F.,
Freitas Larissa
Publication year - 2020
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201900361
Subject(s) - isopropyl , lipase , chemistry , divinylbenzene , factorial experiment , biocatalysis , polymer , matrix (chemical analysis) , styrene , isothermal process , chemical engineering , chromatography , continuous stirred tank reactor , organic chemistry , catalysis , copolymer , thermodynamics , enzyme , mathematics , reaction mechanism , statistics , physics , engineering
Penicillium camemberti lipase immobilized on a magnetized poly(styrene‐ co ‐divinylbenzene) was used as a biocatalyst for isopropyl palmitate synthesis. The reaction conditions were determined by 2 2 factorial central composite design. A mathematical model based on a simplified kinetic approach was developed to describe the system and validated with the experimental data. An assay carried out in a stirred‐tank reactor confirmed the proposed model. The ester was purified and the properties such as density and water content were similar to those found in commercially available isopropyl palmitate.