Premium
Modular Manufacturing Platform for Continuous Synthesis and Analysis of Versatile Nanomaterials
Author(s) -
Bomhard Sibylle,
Schramm Jonas,
Bleul Regina,
Thiermann Raphael,
Höbel Peter,
Krtschil Ulrich,
Löb Patrick,
Maskos Michael
Publication year - 2019
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201900115
Subject(s) - modular design , microreactor , process engineering , nanotechnology , nanomaterials , filtration (mathematics) , microfluidics , materials science , computer science , engineering , chemistry , biochemistry , statistics , mathematics , operating system , catalysis
Nanoparticular materials have a great potential in various fields including technical and biomedical applications; to meet the specific requirements, a good control over the particle characteristics is mandatory. Addressing this, a modular system for the automated and continuous synthesis, workup, and analysis of a broad range of nanoparticles was developed. Application examples of inorganic (silica) and organic (polymersomes, niosomes) nanoparticles demonstrate the versatility of the production platform. Modules for downstream processing via a falling‐film microreactor or tangential flow filtration are presented. The hydrodynamic size as a key parameter is acquired in real time, with an inline dynamic light scattering device. All modules are controlled and operated by a process control system.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom