Premium
Mahkota Dewa Subcritical Water Extraction Process: Experimental and Molecular Dynamics Simulation Study
Author(s) -
Hashim Nurmaryam Aini,
Mudalip Siti Kholijah Abdul,
Harun Noorlisa,
Man Rohaida Che,
Sulaiman Siti Zubaidah,
Arshad Zatul Iffah Mohd,
Shaarani Shalyda M.,
Azmir Jannatul
Publication year - 2019
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201800638
Subject(s) - mangiferin , extraction (chemistry) , chemistry , chromatography , thermal diffusivity , yield (engineering) , materials science , thermodynamics , physics , metallurgy
Subcritical water extraction and molecular dynamics simulation were performed to investigate mangiferin and antioxidant extraction from Mahkota Dewa fruits at different operating temperatures. The mangiferin yield and antioxidant activity were analyzed using high‐performance liquid chromatography and 2‐diphenyl‐1‐picrylhydrazyl assay method, respectively. The diffusivity and intermolecular interactions were determined by mean squared displacement ( MSD ) and radial distribution function (RDF) analysis, respectively. The temperature exerts a momentous effect on mangiferin yield and antioxidant activity of the extract. The MSD result showed an increment in diffusivity coefficient of mangiferin with temperature. The RDF analysis revealed hydrogen bonding formations between mangiferin and water through O H2O • • H MR4(OH1) interaction that plays a role in the extraction process.