Bromination of Aromatic Compounds using Bromine in a Microreactor | Zendy

Deng Qiulin | Zendy; Shen Ruwei | Zendy; Ding Rong | Zendy; Zhang Lixiong | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Bromination of Aromatic Compounds using Bromine in a Microreactor

Author(s) -

Deng Qiulin,

Shen Ruwei,

Ding Rong,

Zhang Lixiong

Publication year - 2016

Publication title -

chemical engineering and technology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.403

H-Index - 81

eISSN - 1521-4125

pISSN - 0930-7516

DOI - 10.1002/ceat.201400723

Subject(s) - microreactor , reagent , halogenation , bromine , catalysis , chemistry , combinatorial chemistry , continuous flow , fluorescence , flow chemistry , organic chemistry , engineering , biochemical engineering , physics , quantum mechanics

2,4,5‐Trifluorobromobenzene is a valuable intermediate with important application in the synthesis of biologically active peptides and fluorescent reagents. A continuous‐flow system has been successfully developed for the synthesis of 2,4,5‐trifluorobromobenzene in a microreactor using FeBr 3 as a catalyst, which is steadily generated in situ from the reaction of Br 2 and Fe. The procedure is efficient and easy‐to‐handle, and 2,4,5‐trifluorobromobenzene can be obtained within minutes in high yields.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research