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Development of a CFD Model of Bubble Column Bioreactors: Part One – A Detailed Experimental Study
Author(s) -
McClure D. D.,
Kavanagh J. M.,
Fletcher D. F.,
Barton G. W.
Publication year - 2013
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201300544
Subject(s) - sparging , bubble , bioreactor , air water , air sparging , fermentation , air bubble , mechanics , chemistry , computational fluid dynamics , materials science , environmental science , chromatography , chemical engineering , engineering , physics , food science , biology , ecology , organic chemistry , contamination , environmental remediation
The holdup and bubble size distribution (BSD) in bubble columns using both air/water and an industrially relevant air/fermentation media system are investigated. It was found that the BSD in the air/fermentation media system was quite narrow and did not change with height. In contrast, the BSD in the air/water system varied considerably with height depending on the sparger design used. Holdup measurements were also performed for different superficial velocities. The holdup in the air/fermentation media system was greater than that for the air/water system, a result attributed to the presence of surface‐active compounds in the fermentation media.