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Mixing Analysis for a Fermentation Broth of the Fungus Beauveria bassiana under Different Hydrodynamic Conditions in a Bioreactor
Author(s) -
NúñezRamírez D. M.,
ValenciaLópez J. J.,
Calderas F.,
SolísSoto A.,
LópezMiranda J.,
MedranoRoldán H.,
MedinaTorres L.
Publication year - 2012
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201200130
Subject(s) - rushton turbine , impeller , continuous stirred tank reactor , draft tube , mechanics , bioreactor , laminar flow , computational fluid dynamics , non newtonian fluid , materials science , rheology , mixing (physics) , thermodynamics , chemistry , physics , engineering , chemical engineering , organic chemistry , quantum mechanics
The performances of radial‐axial flow (Rushton‐Maxflo impellers) and axial‐radial flow (Maxflo‐Rushton impellers) mixers in the laminar‐transitional flow regime were experimentally and numerically investigated with Newtonian and non‐Newtonian fluids. The rheological properties for a fermentation broth consisting of the fungus Beauveria bassiana were studied under different hydrodynamic conditions in these systems. The bioreactor was a continuous stirred‐tank reactor (CSTR), set at different stirring velocities. The rheology of the systems exhibited shear‐thinning behavior which was modeled with the power law model. The experimental hydrodynamics and configuration modes were compared and simulated with a model fluid system and by numerical criteria (computational fluid dynamics). The R‐M mode was found to be more efficient than the M‐R rotating mode in terms of energy and homogenization time. The results will help in the optimization of scale‐up production of these fungi.