Premium
Simulated Moving Bed Chromatography: From Concept to Proof‐of‐Concept
Author(s) -
Sá Gomes P.,
Rodrigues A. E.
Publication year - 2012
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201100281
Subject(s) - simulated moving bed , process (computing) , proof of concept , unit operation , process engineering , scale (ratio) , unit (ring theory) , work (physics) , relevance (law) , computer science , chemistry , chromatography , engineering , mathematics , chemical engineering , mechanical engineering , adsorption , physics , organic chemistry , quantum mechanics , operating system , law , political science , mathematics education
This work presents a comprehensive insight about simulated moving bed (SMB) technology, from concept to unit operation and process demonstration. A particular relevance is given to SMB nonconventional modes of operation, modeling, and design of SMB‐based separations as well as to the construction and operation of SMB units. A conventional separation of a racemic mixture of ( S , R )‐α‐tetralol by means of the FlexSMB‐LSRE® unit is addressed to better exemplify a state‐of‐the‐art SMB lab‐scale process development and demonstration.