Premium
Plant Extraction with Aqueous Two‐Phase Systems
Author(s) -
Schneider P.,
Bischoff F.,
Müller U.,
Bart H.J.,
Schlitter K.,
Jordan V.
Publication year - 2011
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201000420
Subject(s) - ursolic acid , triterpene , extraction (chemistry) , aqueous solution , chemistry , terpene , oleanolic acid , chromatography , mesophase , aqueous two phase system , pulmonary surfactant , phase (matter) , organic chemistry , biochemistry , medicine , alternative medicine , pathology
Abstract The extraction of phytochemicals from plants and their downstream processing is often associated with solvents, which are problematical with respect to health, safety, and environment. An alternative approach is the extraction with aqueous two‐phase systems, which offers a benign environment for complex molecular structures. Particularly nonionic surfactants like, e.g., Genapol® X‐080 and Tween® 65 in high concentrations in water can be used to form aqueous two‐phase systems. Sage ( Salvia triloba ) is used as a model plant, since it contains a relatively high concentration of the two triterpenes oleanolic acid (OA) and ursolic acid (UA), which are interesting due to their wide range of biological effects. Kinetic experiments have shown that an extractive isolation of triterpene acids using such mesophase systems is possible.