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Selected Examples of High‐Pressure Reactions in Glass Microreactors
Author(s) -
Verboom W.
Publication year - 2009
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.200900369
Subject(s) - microreactor , supercritical fluid , bar (unit) , chemistry , capillary action , chemical engineering , materials science , organic chemistry , catalysis , composite material , physics , meteorology , engineering
Recent examples of high‐pressure organic reactions in (flow) glass microreactors of micrometer dimensions are described. Different types of reactions such as Diels‐Alder and nucleophilic aromatic substitution reactions performed in a capillary microreactor gave rate enhancements of 1.5–2.7 at 600 bar. Specifically designed flow glass microreactors, that withstand pressures of 140–690 bar, were used to study Diels‐Alder and oxidation reactions. The use of supercritical fluids gives rise to considerable rate enhancements, while the use of a transparent microreactor allows to visualize phase transitions.