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A Computational Fluid Dynamics Study of Binary Adsorption Separation in Chromatography
Author(s) -
Wu Y.X.,
Yu H.W.,
Ching C.B.
Publication year - 2004
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.200301985
Subject(s) - computational fluid dynamics , simulated moving bed , adsorption , elution , nonlinear system , chromatography , separation process , chemistry , binary number , inlet , dispersion (optics) , computer simulation , materials science , mechanics , mathematics , engineering , physics , mechanical engineering , organic chemistry , arithmetic , optics , quantum mechanics
FEMLAB software was applied to incorporate computational fluid dynamics (CFD) into the simulation of the adsorption‐separation process in chromatography. Simulations of both linear and nonlinear processes demonstrated that significant dispersion retarded the separation processes, and that a small inlet induced curved solute concentration profiles, resulting in peak tailing of the elution chromatogram. The linear simulation visually confirmed that a small Stanton number might be another factor for peak tailing. For cases with a reasonably small Stanton number, peak tailing became more serious with decreasing Stanton number. Comparisons between the results of the CFD simulation of the nonlinear case, the corresponding conventional 1‐D simulation and the experimental result lead to the conclusion that the CFD simulation is useful for a better understanding of the dynamic adsorption and separation process in a chromatographic column.