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Front Cover: The Effect of Visible Light on the Catalytic Activity of PLP‐Dependent Enzymes (ChemCatChem 10/2021)
Author(s) -
Gerlach Tim,
Nugroho David Limanhadi,
Rother Dörte
Publication year - 2021
Publication title -
chemcatchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.202100540
Subject(s) - enzyme , front cover , cofactor , catalysis , chemistry , cover (algebra) , photochemistry , sunlight , biocatalysis , biochemistry , optics , physics , reaction mechanism , mechanical engineering , engineering
The Front Cover indicates the effect that especially blue light exposure, but also ordinary laboratory or sunlight can have on the activity of PLP‐dependent enzymes. In their Full Paper, T. Gerlach et al. show that most of the PLP‐dependent enzymes tested showed a significant loss of activity upon illumination. Consequently, by carrying out the enzyme production and reaction in the dark, and in particular by preserving the cofactor PLP from illumination, the catalytic activity could be increased immensely, in one case up to tenfold. That the effect of light varies with the choice of PLP‐dependent enzyme was demonstrated by the fact that one enzyme was completely resistant to any type of illumination.More information can be found in the Full Paper by T. Gerlach et al.