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Tandem Synthesis of ϵ‐Caprolactam from Cyclohexanone by an Acidified Metal‐organic Framework
Author(s) -
Zhang Biying,
Li Xinle,
Chen Jingwen,
Liu Tianqing,
Cruz Andrew,
Pei Yuchen,
Chen Minda,
Wu Xun,
Huang Wenyu
Publication year - 2021
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.202100425
Subject(s) - caprolactam , tandem , beckmann rearrangement , phosphotungstic acid , chemistry , cyclohexanone , metal organic framework , catalysis , yield (engineering) , cyclohexanone oxime , organic synthesis , cascade reaction , organic chemistry , combinatorial chemistry , materials science , adsorption , metallurgy , composite material
Tandem synthesis of ϵ‐caprolactam, one of the largest scaled commercial chemicals, is highly desired from the viewpoint of cost, energy, and environment. However, relevant studies have remained largely underexplored. By using a one‐pot strategy, we encapsulated phosphotungstic acid (PTA) into a chromium terephthalate metal‐organic framework (MOF), MIL‐101, for the efficient tandem conversion of cyclohexanone to ϵ‐caprolactam. The highly dispersed PTA in the MOF matrix showed a high yield of ϵ‐caprolactam through a tandem oximation‐Beckmann rearrangement reaction at 100 °C for 12 h. Moreover, MIL‐101‐PTA was recycled three times, with only a slight loss in their catalytic performance. To the best of our knowledge, this represents the first report using acidified MOF for a tandem oximation‐Beckmann rearrangement reaction.