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Cover Feature: Substrate‐Controlled Cyclopropanation Reactions of Glycals with Aryl Diazoacetates (ChemCatChem 16/2020)
Author(s) -
Guo Yujing,
Pei Chao,
Koenigs Rene M.
Publication year - 2020
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.202001194
Subject(s) - cyclopropanation , rhodium , carbene , acceptor , reactivity (psychology) , cyclopropane , chemistry , glucal , aryl , catalysis , medicinal chemistry , organic chemistry , ring (chemistry) , physics , alkyl , medicine , alternative medicine , pathology , condensed matter physics
The Cover Feature shows an achiral rhodium(II) complex that undergoes formation of rhodium donor/acceptor carbene complexes. This rhodium complex can react in a stereoselective cyclopropanation reaction with glucal derivatives giving two different cyclopropane products depending on the acceptor group of the carbene. In their Communication, Y. Guo et al. describe the application of this cyclopropanation with a broad range of different glucal derivatives and donor/acceptor diazoalkanes. Theoretical calculations are then used to rationalize for the distinct reactivity of aryldiazoacetates vs. trifluoromethylated donor/acceptor diazoalkanes to provide an understanding of the different pathways in this cyclopropanation reaction. More information can be found in the Communication by Y. Guo et al.