Nickel‐Catalyzed Synthesis of  N ‐(Hetero)aryl Carbamates from Cyanate Salts and Phenols Activated with Cyanuric Chloride | Zendy

Dindarloo Inaloo Iman | Zendy; Esmaeilpour Mohsen | Zendy; Majnooni Sahar | Zendy; Reza Oveisi Ali | Zendy

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Nickel‐Catalyzed Synthesis of N ‐(Hetero)aryl Carbamates from Cyanate Salts and Phenols Activated with Cyanuric Chloride

Author(s) -

Dindarloo Inaloo Iman,

Esmaeilpour Mohsen,

Majnooni Sahar,

Reza Oveisi Ali

Publication year - 2020

Publication title -

chemcatchem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.497

H-Index - 106

eISSN - 1867-3899

pISSN - 1867-3880

DOI - 10.1002/cctc.202000876

Subject(s) - cyanuric chloride , aryl , chemistry , catalysis , reagent , cyanate , organic chemistry , nickel , phenol , chloride , phenols , melamine , aniline , triazine , combinatorial chemistry , alkyl

A simple and efficient domino reaction has been designed and employed for the one‐pot synthesis of N ‐(hetero)aryl carbamates through the reaction between alcohols and in‐situ produced (hetero)aryl isocyanates in the presence of a nickel catalyst. The phenolic C−O bond was activated via the reaction of phenol with cyanuric chloride (2,4,6‐trichloro‐1,3,5‐triazine (TCT)) as an inexpensive and readily available reagent. This strategy provides practical access to N ‐(hetero)aryl carbamates in good yields with high functional groups compatibility.

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