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Rh(III)‐Catalyzed [4+1] Cyclization of Sulfoxonium Ylides and Anthranils for Accessing N ‐Arylisatins
Author(s) -
Zhou Peng,
Yang WeiTao,
Li Guigen,
Hao WenJuan,
Jiang Bo
Publication year - 2020
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.202000640
Subject(s) - annulation , catalysis , rhodium , ring (chemistry) , chemistry , aldehyde , medicinal chemistry , combinatorial chemistry , stereochemistry , organic chemistry
A rhodium(III)‐catalyzed [4+1] cyclization between aroyl sulfoxonium ylides and anthranils has been developed, offering a wide range of new aldehyde‐containing N‐arylisatins in good to excellent yields. The highlight of this reaction shows the construction of two C−N and one C=O bonds through [4+1] annulation consisted of C−H activation, ring opening of anthranils and oxygen insertion.
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