Premium
Palladium‐Catalyzed peri ‐Selective C−H Fluoroalkoxylation of Aryl Sulfoxides
Author(s) -
Sato Tomohiko,
Nogi Keisuke,
Yorimitsu Hideki
Publication year - 2020
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.202000485
Subject(s) - palladium , aryl , sulfoxide , catalysis , chemistry , medicinal chemistry , peri , organic chemistry , combinatorial chemistry , philosophy , alkyl , theology
Sulfinyl‐directed peri ‐selective C−H fluoroalkoxylation of aryl sulfoxides with fluorinated alcohols has been developed. By means of a palladium catalyst and PhI(OAc) 2 as an oxidant, a range of fluoroalkoxy groups can be installed onto the peri position of aryl sulfoxides. The remaining sulfinyl groups on the fluoroalkoxylation products further promote Pummerer‐based C−H functionalizations.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom