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Front Cover: Towards Preparative Chemoenzymatic Oxidative Decarboxylation of Glutamic Acid (ChemCatChem 8/2020)
Author(s) -
Xu Xiaomin,
But Andrada,
Wever Ron,
Hollmann Frank
Publication year - 2020
Publication title -
chemcatchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.202000250
Subject(s) - decarboxylation , chemistry , catalysis , oxidative decarboxylation , biocatalysis , glutamic acid , front cover , organic chemistry , amino acid , combinatorial chemistry , reaction mechanism , biochemistry , cover (algebra) , mechanical engineering , engineering
The Front Cover shows the concept of the chemoenzymatic conversion of glutamic acid into 3‐cyano propanoic acid using the vanadium‐dependent haloperoxidase from Curvularia inaequalis (CiVCPO). CiVCPO catalyses the formation of hypohalites from H 2 O 2 and halides, which then mediate the oxidative decarboxylation of amino acids such as glutamic acid. In their Communication, X. Xu, A. But et al. outline the factors influencing the efficiency of this transformation. The high product titres achieved and the excellent catalytic performance of the biocatalyst point towards preparative‐scale application of this reaction and valorisation of agricultural waste‐derived glutamic acid into a building block for chemical synthesis.More information can be found in the Communication by X. Xu, A. But et al..