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Immobilised Enzymes for Sesquiterpene Synthesis in Batch and Flow Systems
Author(s) -
Valikhani Donya,
Srivastava Prabhakar Lal,
Allemann Rudolf K.,
Wirth Thomas
Publication year - 2020
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201902135
Subject(s) - sesquiterpene , bioconversion , chemistry , enzyme , flow chemistry , catalysis , biotransformation , enzyme catalysis , organic chemistry , stereochemistry , fermentation
Abstract Sesquiterpene synthases catalyse the bioconversion of farnesyl diphosphate into sesquiterpenes. The immobilisation of sesquiterpene synthases on controlled porosity glass through metal‐ion affinity binding is reported. The immobilised sesquiterpene synthases were able to maintain 50 % catalytic activity for at least 50 cycles under continuous flow conditions.