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Reductive Cycloisomerization of Diynes by Supported Palladium Catalysts and Subsequent [4+2] Cycloaddition for One‐Pot Synthesis of Cyclohexenes
Author(s) -
Miura Hiroki,
Tanaka Yumi,
Nakahara Karin,
Shishido Tetsuya
Publication year - 2020
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201901423
Subject(s) - cycloisomerization , cycloaddition , catalysis , chemistry , palladium , cyclohexene , intermolecular force , organic chemistry , photochemistry , combinatorial chemistry , medicinal chemistry , molecule
Abstract : Supported Pd nanoparticles catalyzed the reductive cycloisomerization of diynes to give 1,3‐dienes, and subsequent intermolecular [4+2] cycloaddition with dienophiles led to cyclohexene derivatives. Various diynes and dienophiles participated in the one‐pot reaction to give the corresponding products in good to high yields. Al 2 O 3 ‐supported Pd catalysts were highly tolerant toward air and reusable.