Premium
Enhancing Ligand‐Free Fe‐Catalyzed Aminocarbonylation of Alkynes by ZrF 4
Author(s) -
Huang Zijun,
Dong Yanan,
Li Yudong,
Makha Mohamed,
Li Yuehui
Publication year - 2019
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201900995
Subject(s) - catalysis , amine gas treating , alkyne , chemistry , fluoride , ligand (biochemistry) , zirconium , combinatorial chemistry , organic chemistry , inorganic chemistry , biochemistry , receptor
Zirconium fluoride was utilized to promote efficiently iron‐catalyzed aminocarbonylation between alkynes and amines without the use of extra ligands. In particular, this new system is applicable to a wide range of amine and alkyne substrates affording α , β ‐unsaturated amides in good to excellent yields. Preliminary mechanistic studies reveal the activation model involving interactions of ZF 4 with both iron catalyst and amine substrates.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom