Premium
Cover Feature: Chloramphenicol Base: A New Privileged Chiral Scaffold in Asymmetric Catalysis (ChemCatChem 8/2019)
Author(s) -
Xiao YouCai,
Chen FenEr
Publication year - 2019
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201900586
Subject(s) - chemistry , bifunctional , catalysis , oxazoline , combinatorial chemistry , ligand (biochemistry) , chloramphenicol , scaffold , stereochemistry , hydrogen bond , organic chemistry , biochemistry , molecule , antibiotics , computer science , receptor , database
The Cover Feature shows a Chinese incense burner with the chloramphenicol base scaffold at the base and surrounded by several substrates. In their Minireview, Y.‐C. Xiao and F.‐E. Chen show how the chloramphenicol base (ANP) scaffold can be easily transformed to a variety of chiral ligands (amino alcohol, Schiff base and oxazoline‐containing ligand) and organocatalyst (hydrogen bonding‐based bifunctional catalyst and phase transfer catalyst). These ANP derivatives show high proficient in a wide range of asymmetric transformations, especially for the synthesis of chiral pharmaceuticals. More information can be found in the Minireview by Y.‐C. Xiao and F.‐E. Chen on page 2043 in Issue 8, 2019 (DOI: 10.1002/cctc.201900150).