Planar‐Chiral [2.2]Paracyclophane‐Based Pyridonates as Ligands for Tantalum‐Catalyzed Hydroaminoalkylation | Zendy

Braun Carolin | Zendy; Nieger Martin | Zendy; Bräse Stefan | Zendy; Schafer Laurel L. | Zendy

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Planar‐Chiral [2.2]Paracyclophane‐Based Pyridonates as Ligands for Tantalum‐Catalyzed Hydroaminoalkylation

Author(s) -

Braun Carolin,

Nieger Martin,

Bräse Stefan,

Schafer Laurel L.

Publication year - 2019

Publication title -

chemcatchem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.497

H-Index - 106

eISSN - 1867-3899

pISSN - 1867-3880

DOI - 10.1002/cctc.201900416

Subject(s) - tantalum , catalysis , chelation , chemistry , planar chirality , combinatorial chemistry , planar , stereochemistry , medicinal chemistry , enantioselective synthesis , organic chemistry , computer graphics (images) , computer science

By using planar chiral [2.2]paracyclophane‐containing N , O ‐chelating ligands for tantalum‐catalyzed hydroaminoalkylation, one of the most versatile catalytic systems for this reaction to date was obtained. Convenient C sp3 −C sp3 bond formation of amines with terminal and internal alkenes was enabled by the same in situ synthesized catalytic system of [2.2]paracyclophane‐based pyridonates and Ta(CH 2 TMS) 3 Cl 2 that shows also very promising results for N ‐containing heterocycles.

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