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Planar‐Chiral [2.2]Paracyclophane‐Based Pyridonates as Ligands for Tantalum‐Catalyzed Hydroaminoalkylation
Author(s) -
Braun Carolin,
Nieger Martin,
Bräse Stefan,
Schafer Laurel L.
Publication year - 2019
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201900416
Subject(s) - tantalum , catalysis , chelation , chemistry , planar chirality , combinatorial chemistry , planar , stereochemistry , organic chemistry , enantioselective synthesis , computer science , computer graphics (images)
By using planar chiral [2.2]paracyclophane‐containing N , O ‐chelating ligands for tantalum‐catalyzed hydroaminoalkylation, one of the most versatile catalytic systems for this reaction to date was obtained. Convenient C sp3 −C sp3 bond formation of amines with terminal and internal alkenes was enabled by the same in situ synthesized catalytic system of [2.2]paracyclophane‐based pyridonates and Ta(CH 2 TMS) 3 Cl 2 that shows also very promising results for N ‐containing heterocycles.