Premium
Manganese‐Catalyzed Transfer Hydrogenation of Aldimines
Author(s) -
Wei Duo,
BruneauVoisine Antoine,
Dubois Maxime,
Bastin Stéphanie,
Sortais JeanBaptiste
Publication year - 2019
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201900314
Subject(s) - aldimine , manganese , yield (engineering) , catalysis , transfer hydrogenation , chemistry , phosphine , medicinal chemistry , organic chemistry , polymer chemistry , materials science , metallurgy , ruthenium
The reduction of imines to amines via transfer hydrogenation was achieved promoted by phosphine‐free manganese(I) catalyst. Using isopropanol as reductant, in the presence of t BuOK (4 mol %) and manganese complex [Mn(CO) 3 Br(κ 2 N,N‐PyCH 2 NH 2 )] (2 mol %), a large variety of aldimines (30 examples) were typically reduced in 3 hours at 80 °C with good to excellent yield.