Premium
Assembling Two‐Phase Enzymatic Cascade Pathways in Pickering Emulsion
Author(s) -
Pan Yongchun,
Qiu Wu,
Li Qin,
Zhu Shuihong,
Lin Changxu,
Zeng Wenbin,
Xiong Xueqing,
Liu Xiang Yang,
Lin Youhui
Publication year - 2019
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201900098
Subject(s) - pickering emulsion , microreactor , cascade , nanotechnology , cascade reaction , emulsion , biocatalysis , materials science , catalysis , chemistry , organic chemistry , reaction mechanism , nanoparticle , chromatography
The design of enzymatic cascade pathways in biphasic systems with high efficiency is still a big challenge. Herein, we report a simple and efficient strategy for one‐pot biphasic tandem reactions by positioning distinct biocatalysts in spatially separate domains of Pickering emulsion. Due to the large interfacial area and the stability of Pickering interfacial biocatalysts, the as‐obtained Pickering emulsion system was confirmed as a nice microreactor with highly enhanced catalytic performance. Furthermore, in this hybrid catalytic system, unconventional computing relied on enzymatic cascade reactions can be performed. Such Pickering emulsion‐based logic system offers several distinctive advantages, including less “cross‐talk” and signal amplification. We believe that our result will have critical applications in future biocatalysis, nanomachines, smart diagnostics, intelligent drug delivery, nanomechanical, and electronics.