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Visible Light Mediated C(sp 3 )‐H Alkenylation of Cyclic Ethers Enabled by Aryl Ketone
Author(s) -
Zhang Mengmeng,
Yang Liming,
Yang Hui,
An Guanghui,
Li Guangming
Publication year - 2019
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201802079
Subject(s) - chemistry , ether , aryl , reagent , ketone , nitration , medicinal chemistry , photochemistry , organic chemistry , alkyl
C−H alkenylation of cyclic ethers (THF, 1,4‐dioxane) using the readily available nitroalkenes as the alkenylating reagents has been developed. It allows the rapid access to the α ‐alkenyl ethers with high E ‐selectivity. The previous inaccessible α ‐dienyl ethers are successfully obtained. Acyclic ether can also participate in this alkenylation process. The mechanism study reveals that alkenylation proceeded through a proton coupled electron transfer (PCET) process with a de‐nitration.