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Hemoglobin: A New Biocatalyst for the Synthesis of 2‐substituted Benzoxazoles via Oxidative Cyclization
Author(s) -
Li Fengxi,
Li Zhengqiang,
Tang Xuyong,
Cao Xinyu,
Wang Chunyu,
Li Jialin,
Wang Lei
Publication year - 2019
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201801760
Subject(s) - oxidative phosphorylation , biocatalysis , chemistry , hemoglobin , combinatorial chemistry , catalysis , organic chemistry , reaction mechanism , biochemistry
Efficient and mild synthesis of a series of 2‐substituted benzoxazoles via oxidative cyclization catalyzed by hemoglobins reported here for the first time. Satisfactory yields (84 %–97 %) and mild reaction conditions make this method highly viable for practical applications.