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Cover Feature: Aminocarbonylation of Aryl Halides to Produce Primary Amides by Using NH 4 HCO 3 Dually as Ammonia Surrogate and Base (ChemCatChem 22/2017)
Author(s) -
Wang DongLiang,
Liu Huan,
Yang Da,
Wang Peng,
Lu Yong,
Liu Ye
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201701772
Subject(s) - aryl , halide , chemistry , ammonia , hydrolysis , base (topology) , combinatorial chemistry , medicinal chemistry , inorganic chemistry , organic chemistry , mathematical analysis , alkyl , mathematics
The Cover Feature shows a Pd‐catalyzed aminocarbonylation of aryl halides with solid ammonia surrogate NH 4 HCO 3 . In their Full Paper, D.‐L. Wang et al. describe the dual role of NH 4 HCO 3 as ammonia surrogate and base to scavenge the released acid (HX). The use of cheap and solid NH 4 HCO 3 not only made the reaction manipulation simplified and inodorous, but also favored the aminocarbonylation of aryl halides over the subsequent dehydration or hydrolysis of the formed amides owing to its mild basicity. More information can be found in the Full Paper by D.‐L. Wang et al. on page 4206 in Issue 22, 2017 (DOI: 10.1002/cctc.201700893).