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Copper‐Catalyzed C2 and C3 Phosphonation of Benzofuran and Benzothiophene with Trialkyl Phosphites
Author(s) -
Wang Yufeng,
Yang Yajie,
Jie Kun,
Huang Ling,
Guo Shengmei,
Cai Hu
Publication year - 2018
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201701361
Subject(s) - benzothiophene , benzofuran , chemistry , furan , catalysis , organic chemistry , copper , thiophene
A strategy for the selective phosphonation of benzofuran and benzothiophene with trialkyl phosphites was developed. In these reactions, the C−H phosphonation of benzofurans or benzothiophenes at the C2 or C3 position with trialkyl phosphites was successfully achieved without directing groups by using a copper catalyst. Additionally, the C5 phosphonation of furan was successful under the same conditions.